Sildenafil and tadalafil together: in one prescribed tablet
Do not combine Viagra and Cialis on your own: both labels say combinations with other PDE5 inhibitors were not studied and may lower blood pressure further. A compounded tablet with sildenafil and tadalafil is a separate prescription. Mendoxa's adds apomorphine, from $129 a month if a clinician prescribes.
Start your ED visit From $129/month. If prescribed · Cancel anytime · Available in 49 states (not California).
Can you take Cialis and Viagra together?
The Viagra label says combinations with other PDE5 inhibitors or other ED treatments “have not been studied,” “may further lower blood pressure,” and are “not recommended.” The Cialis label says to tell patients not to take Cialis with other PDE5 inhibitors. So do not stack your own Viagra and Cialis. A compounded combination tablet is a separate prescription, and the clinician weighs these warnings before writing it.
Sildenafil vs tadalafil, side by side
| Sildenafil (Viagra label) | Tadalafil (Cialis label) | |
|---|---|---|
| Usual start | 50 mg as needed | 10 mg as needed, or 2.5 mg daily |
| Range | 25 mg to 100 mg | As needed 5 to 20 mg; daily 2.5 to 5 mg |
| Timing | About 1 hour before; 30 min to 4 h window | Before sex; effect vs placebo up to 36 h |
| Peak level | 30 to 120 min (median 60) | 30 min to 6 h (median 2 h) |
| Half-life | About 4 hours | 17.5 hours |
| Food | With or without food; high-fat meal delays it | Without regard to food |
| Hard stops | Nitrates, riociguat | Nitrates, riociguat |
Mendoxa ED plans and prices
The Mendoxa ED tablet is a compounded rapid-dissolve tablet with sildenafil (the active ingredient in Viagra), tadalafil (the active ingredient in Cialis) and apomorphine. It dissolves under the tongue. The Mendoxa ED page lists a maximum of 1 dose per 24 hours. A licensed clinician decides if it fits you and selects the strength. Compounded medicines are not FDA-approved.
| Plan | 1-month plan | Per tablet | 3-month plan | Per tablet (3 months) |
|---|---|---|---|---|
| 6 tablets / month | $129 | $21.50 | $329 | $18.28 |
| 10 tablets / month | $149 | $14.90 | $379 | $12.63 |
| 20 tablets / month | $179 | $8.95 | $449 | $7.48 |
If prescribed · Cancel anytime · Available in 49 states (not California). Prices from the Mendoxa intake at try.mendoxa.co/f/ed on Oct 17, 2026. The intake always shows the current price.
Combination tablets you can compare
| Mendoxa tablet | Rugiet Ready | BlueChew Gold | |
|---|---|---|---|
| Ingredients | Sildenafil, tadalafil, apomorphine | Sildenafil, tadalafil, apomorphine | Sildenafil, tadalafil, apomorphine, oxytocin |
| Form | Rapid-dissolve tablet | Sublingual troche | Sublingual |
| FDA status | Compounded | Compounded | Compounded |
| Price shown | From $129 for 1 month (6 tablets). 3 months of 20 tablets/month: $449, about $7.48 per tablet | Not on the Ready page | From $7.30 each |
Competitor data from rugiet.com and bluechew.com, opened Oct 17, 2026.
Safety for any combination
The Viagra and Cialis labels list the same hard stops. Do not use them with organic nitrates in any form, or with a guanylate cyclase stimulator such as riociguat. Do not use them if sex is inadvisable because of your heart. Get emergency care for an erection that lasts more than 4 hours. Stop and get care for a sudden loss of vision in one or both eyes, or a sudden decrease or loss of hearing.
The FDA label we can cite for apomorphine is APOKYN, a subcutaneous injection for Parkinson's disease “off” episodes. It is not an ED label and it does not set an ED dose. It lists: nausea and vomiting; syncope and low blood pressure on standing; falling asleep during daily activities; painful prolonged erections (reported by 3 of 361 treated men). It says use with 5HT3 antagonists such as ondansetron is contraindicated, after reports of profound hypotension and loss of consciousness. Alcohol and sublingual nitroglycerin made its blood-pressure drop larger.
The FDA says compounded drugs are not FDA-approved, and that the FDA does not verify their safety, effectiveness or quality before they are marketed. That applies to the Mendoxa tablet and to every other compounded ED product on this page.
FAQ
Can you take Cialis and Viagra together?
Not on your own. The Viagra label says such combinations were not studied, may further lower blood pressure, and are not recommended. The Cialis label says not to take it with other PDE5 inhibitors.
Is there a tablet with sildenafil and tadalafil?
Yes, as a compounded prescription. The Mendoxa tablet combines sildenafil, tadalafil and apomorphine. It is not FDA-approved, and a clinician decides if it fits.
What is the difference between sildenafil and tadalafil?
On their labels, sildenafil has a half-life of about 4 hours and a 30-minute-to-4-hour dosing window. Tadalafil has a 17.5-hour half-life and an effect versus placebo up to 36 hours.
How much is the Mendoxa combination tablet?
$129 for 1 month (6 tablets). The 3-month plan with 20 tablets per month (60 tablets total) is $449, about $7.48 per tablet.
Start your ED visit: plans and prices
The Mendoxa ED tablet is a compounded rapid-dissolve tablet with sildenafil (the active ingredient in Viagra), tadalafil (the active ingredient in Cialis) and apomorphine. It dissolves under the tongue. The Mendoxa ED page lists a maximum of 1 dose per 24 hours. A licensed clinician decides if it fits you and selects the strength. Compounded medicines are not FDA-approved.
| Plan | 1-month plan | Per tablet | 3-month plan | Per tablet (3 months) |
|---|---|---|---|---|
| 6 tablets / month | $129 | $21.50 | $329 | $18.28 |
| 10 tablets / month | $149 | $14.90 | $379 | $12.63 |
| 20 tablets / month | $179 | $8.95 | $449 | $7.48 |
If prescribed · Cancel anytime · Available in 49 states (not California). Prices from the Mendoxa intake at try.mendoxa.co/f/ed on Oct 17, 2026. The intake always shows the current price.
References
- DailyMed: VIAGRA (sildenafil citrate) tablet, film coated, label revised 12/2017. Accessed Oct 17, 2026.
- DailyMed: CIALIS (tadalafil) tablet, film coated, label revised 3/2026. Accessed Oct 17, 2026.
- DailyMed: APOKYN (apomorphine hydrochloride) injection, label revised 6/2022. Accessed Oct 17, 2026.
- FDA (Drugs@FDA): VIAGRA prescribing information, NDA 020895. Accessed Oct 17, 2026.
- FDA (Drugs@FDA): CIALIS prescribing information, NDA 021368. Accessed Oct 17, 2026.
- FDA: Compounding and the FDA, questions and answers. Accessed Oct 17, 2026.
- Rugiet: Ready product page. Accessed Oct 17, 2026.
- BlueChew: GOLD product page. Accessed Oct 17, 2026.
- Mendoxa ED care (product, format, max 1 dose per 24 hours). Accessed Oct 17, 2026.
- Mendoxa ED intake: plan prices (term_options). Accessed Oct 17, 2026.
About Mendoxa
Mendoxa (mendoxa.co) is a US telehealth brand. Licensed clinicians in the LocumTele network review each online visit, and prescriptions are filled by Rush Pharmacy, a licensed US pharmacy. Available in 49 states (not California).
- A licensed clinician reviews every visit and can say no. A prescription is not automatic.
- A compounded medicine is not an FDA-approved finished product.
- Plans: 1 month or 3 months, from $129. If prescribed · Cancel anytime · Available in 49 states (not California).
Compounded medication prescribed only if a licensed U.S. clinician decides it is appropriate. Not FDA-approved as a finished product. Not available in California. This site is not for emergencies. Call 911 if you need urgent care.